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Mon. 11 Jun, 2012

UPSC Half-Time Seminar: Malgorzata Pietrzykowska

Mon. 11 Jun, 2012 15:00 - 16:00
UPSC Half-Time Seminar
Speaker:
Malgorzata Pietrzykowska

Title: 
Is there a functional difference between Lhcb1 and Lhcb2?

Place Lilla hörsalen

Tue. 12 Jun, 2012

Seminar - Beverley Green: Algal genomics and the evolution of light-harvesting antennae

Tue. 12 Jun, 2012 14:00 - 15:00

Department of Chemistry

 

Seminar

Beverley Green

University of British Columbia, Vancouver, Canada

 

Title: Algal genomics and the evolution of light-harvesting antennae

 

Host: Christiane Funk

Place: Lilla Hörsalen, KB3A9, KBC

 

Abstract:

The ocean is the new frontier in genomics research! The marine algae are particularly important because of their influence on global climate as well as their major contribution to the oceanic food web. The recently sequenced genomes of a number of these algae have illuminated the wide range of photosynthetic biodiversity in the ocean. Particularly interesting are the algae with chlorophyll a/c light-harvesting antennas, such as the diatoms and brown algae, which acquired their plastids by secondary endosymbiosis, and have derived new varieties of light-harvesting antennas.

Wed. 13 Jun, 2012

Cutting Edge Seminar - Theodorus Meuwissen: Prediction of total genetic value using whole genome sequence data

Wed. 13 Jun, 2012 10:00 - 11:00
UPSC Cutting Edge Seminar

Theodorus Meuwissen
Department of Animal and Aquacultural Sciences
The Norwegian University of Life Sciences (UMB), Ås, Norway  

Title:
Prediction of total genetic value using whole genome sequence data

Place: Stora hörsalen, KBC

Thu. 14 Jun, 2012

There are no events on this day.

Fri. 15 Jun, 2012

Seminar - Kazuya Kikuchi: Design, synthesis and biological application of in vivo imaging probes with tunable chemical switches

Fri. 15 Jun, 2012 13:30 - 14:30

Seminar

professor Kazuya Kikuchi

Osaka University

Graduate School of Engineering

WPI-Immunology Frontier Research Center

Osaka, Japan

 

Title: Design, synthesis and biological application of in vivo imaging probes with tunable chemical switches

 

Host: Gunnar Öquist

Place: KBC, Large Lecture hall "Stora hörsalen"

 

Abstract: 

One of the great challenges in the post-genome era is to clarify the biological significance of intracellular molecules directly in living cells. If we can image a molecule in action, it is possible to acquire biological information, which is unavailable if we deal with cell homogenates. One possible approach is to design and synthesize chemical probes that can convert biological information to chemical output. Protein fluorescent labeling provides an attractive approach to study the localization and function of proteins in living cells. Recently, a specific pair of a protein tag and its ligand has been utilized to visualize a protein of interest (POI). In this method, a POI is fused with a protein tag and the tag is labeled with the ligand connected to a fluorescent molecule. The advantage of this protein labeling system is that a variety of fluorescent molecules are potentially available as labeling reagents, and that the protein tag is conditionally labeled with its fluorescent ligand. I have designed a protein labeling system that allows fluorophores to be linked to POI. The protein tag (BL-tag) is a mutant class A ?-lactamase (TEM-1) modified to be covalently bound to the designed specific labeling probes and the labeling probes is consisted with a ?-lactam ring (ampicillin, cephalosporin) attached to various fluorophores. A fluorogenetic labeling system can be designed using the unique property of cephalosporin, which release leaving group by subsequent reaction after opening the lactam ring. For further sophisticated application, multicolor imaging was done by adopting the colorful fluorophores.

Seminar - Janne Lehtiö: Defining human proteome using high resolution peptide isoelectric focusing coupled to mass spectrometry (HiRIEF-LC-MS) and the application of this method to improve cancer treatment

Fri. 15 Jun, 2012 15:00 - 16:00
Umeå Plant Science Centre
Seminar

Speaker:
Janne Lehtiö
Clinical Proteomics Mass Spectrometry, Karolinska Institutet, SciLifeLab Stockholm
Science for Life Laboratory

Title:
Defining human proteome using high resolution peptide isoelectric focusing coupled to mass spectrometry (HiRIEF-LC-MS) and the application of this method to improve cancer treatment

Place: Lilla hörsalen, KB3A9

Host Anders Nordström

Sat. 16 Jun, 2012

There are no events on this day.

Sun. 17 Jun, 2012

There are no events on this day.